JNK2 cDNA Clone: Expression and Clone Vector / Plasmid

JNK2 cDNA / Gene Overview

MAPK9 gene / cDNA is a protein-coding gene which located on 5q35.3. The MAPK9 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish.199 organisms have orthologs with human gene MAPK9.

JNK2 cDNA / Gene Function

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]

JNK2 cDNA / Gene Sequence

LOCUS
LOCUS NM_001135044 2370 bp mRNA linear PRI 24-JUN-2018
DEFINITION
Homo sapiens mitogen-activated protein kinase 9 (MAPK9), transcript variant JNK2-g, mRNA.
ACCESSION
NM_001135044
VERSION
NM_001135044.1

This sequence information is just for reference only.

JNK2 Family & Reagents

JNK2 Gene family reagents (Mitogen-activated protein kinases)

Approved Symbol Reagent list
MAPK1
MAPK13
MAPK8
Approved Symbol Reagent list
MAPK12
MAPK14
   

JNK2 cDNA / Gene Alias

  • JNK2
  • Jun kinase
  • p54a
  • SAPK

JNK2 cDNA / Gene Expression

Ubiquitous expression in brain (RPKM 22.1), thyroid (RPKM 10.2) and 25 other tissues

Recombinant JNK2 protein citations

Title
Myricetin suppresses differentiation of 3 T3-L1 preadipocytes and enhances lipolysis in adipocytes
Year
2015
Author
Wang, Q;Wang, ST;Yang, X;You, PP;Zhang, W;
Journal
Nutr Res