IRTA1/FCRL4 cDNA Clone: Expression and Clone Vector / Plasmid

IRTA1/FCRL4 cDNA / Gene Overview

FCRL4 cDNA / gene is a gene with protein product which located on 1q23.1. The FCRL4 gene is conserved in chimpanzee, Rhesus monkey, dog, and cow. 77 organisms have orthologs with human gene FCRL4.

IRTA1/FCRL4 cDNA / Gene Function

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

IRTA1/FCRL4 cDNA / Gene Sequence

LOCUS
AF343661 3459 bp mRNA linear PRI 18-JUN-2001
DEFINITION
Homo sapiens immunoglobulin superfamily receptor translocation associated protein 1a (IRTA1) mRNA, complete cds, alternatively spliced.
ACCESSION
AF343661
VERSION
AF343661.1

This sequence information is just for reference only.

IRTA1/FCRL4 Family & Reagents

IRTA1/FCRL4 Gene family reagents (CD molecules)

Approved Symbol Reagent list
CLEC12A
CD209
LAMP2
LAIR2
CD276
CD36
IL2RG
BMPR1B
FGFR4
CD160
Approved Symbol Reagent list
FCER2
CD200
PROM1
IL1R2
IL18R1
TNFRSF18
EpCAM
PLAUR
ICAM4
ICAM3

IRTA1/FCRL4 Gene family reagents (Immunoglobulin like domain containing)

Approved Symbol Reagent list
PECAM1
CEACAM8
FCGR3B
CADM3
ICAM4
CD86
ICAM1
ICAM2
ICAM3
IL6R
Approved Symbol Reagent list
CLMP
CXADR
VSTM1
CD48
LAIR1
IL1RAPL1
MCAM
IL1RAPL2
NECTIN2
CADM4

IRTA1/FCRL4 cDNA / Gene Alias

  • CD307d
  • FCRH4
  • IGFP2
  • IRTA1

IRTA1/FCRL4 cDNA / Gene Expression

Biased expression in lymph node (RPKM 2.4), appendix (RPKM 2.3) and 5 other tissues