ICOS ligand cDNA Clone: Expression and Clone Vector / Plasmid

ICOS ligand cDNA / Gene Overview

ICOSLG gene / cDNA is a protein-coding gene which located on 21q22.3. The ICOSLG gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.156 organisms have orthologs with human gene ICOSLG.

ICOS ligand cDNA / Gene Sequence

LOCUS
LOCUS NM_015259 3320 bp mRNA linear PRI 30-JUN-2018
DEFINITION
Homo sapiens inducible T cell costimulator ligand (ICOSLG), transcript variant 1, mRNA.
ACCESSION
NM_015259
VERSION
NM_015259.5

This sequence information is just for reference only.

ICOS ligand Family & Reagents

ICOS ligand Gene family reagents (CD molecules)

Approved Symbol Reagent list
LAIR1
ICAM4
DPP4
CD300E
PDGFRA
IL12RB1
L1CAM
MPL
TNFRSF10D
TNFSF11
Approved Symbol Reagent list
IL13Ra2
IL10RA
IL6R
CD274
BST1
FGFR3
FCGR3A
FAS
CD37
FGFR1

ICOS ligand Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
SELPLG
CCL4
XCL1
CCL1
CCL24
NTS
FGF2
AGT
XCL2
ICAM1
Approved Symbol Reagent list
CD40LG
C5
CXCL10
INHBB
PROC
PROK1
PTH
FGF7
CXCL2
FLT3LG

ICOS ligand Gene family reagents (V-set domain containing)

Approved Symbol Reagent list
CRTAM
CD226
CD300A
CD83
MCAM
NCR2
SCN2B
HEPACAM
CD300C
TREM2
Approved Symbol Reagent list
CEACAM19
GPA33
SLAMF6
VSIG8
BTN3A2
HepaCAM2
PILRA
PVR
PTGFRN
PIGR

ICOS ligand Gene family reagents (C2-set domain containing)

Approved Symbol Reagent list
CD22
VCAM1
CRTAM
KIRREL3
CD274
NECTIN4
TMEM25
CD276
NECTIN3
PVR
Approved Symbol Reagent list
CD80
CADM1
ALCAM
NECTIN1
BTN3A1
KIRREL2
BCAM
MAG
CD200R1
CD2

ICOS ligand cDNA / Gene Alias

  • B7 homolog 2
  • B7 homologue 2
  • B7H2
  • B7-H2
  • B7-related protein 1
  • B7RP1
  • B7RP-1
  • CD275
  • GL50
  • ICOS-L
  • KIAA0653

ICOS ligand cDNA / Gene Expression

Ubiquitous expression in brain (RPKM 4.2), lymph node (RPKM 3.4) and 23 other tissues

Recombinant ICOS ligand protein citations

Title
ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses.
Year
2017
Author
Lownik, JC;Luker, AJ;Damle, SR;Cooley, LF;El Sayed, R;Hutloff, A;Pitzalis, C;Martin, RK;El Shikh, MEM;Conrad, DH;
Journal
J. Immunol.