FGFR2 Protein

FGFR2 Protein Overview

FGFR2 reagents

BEK, MOUSE, HOMOLOG OF, INCLUDEDFIBROBLAST GROWTH FACTOR RECEPTOR BEK, INCLUDED

FGFR2 protein family

Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.

FGFR2 protein name

Recommended name
Fibroblast growth factor receptor 2
Short name
FGFR-2||KGFR
Aliases
CD332, CEK3, Crouzon syndrome, ECT1, K-SAM, Pfeiffer syndrome, TK14, TK25
Alternative name
K-sam Keratinocyte growth factor receptor CD_antigen: CD332

FGFR2 Gene family protein

FGFR2 Protein Sequence

Species Human FGFR2 protein
Length 821
Mass (Da) 92025
Sequence Human FGFR2 protein sequence
Species Mouse FGFR2 protein
Length 821
Mass (Da) 91984
Sequence Mouse FGFR2 protein sequence
Species
Length
Mass (Da)
Sequence

FGFR2 Protein Molecular Weight & PI

Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD332 antigen) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 22-821 Fibroblast growth factor receptor 2.

Molecular weight (Da)

89745.17

Theoretical pI

5.56

FGFR2 Protein Structure

Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Gain-of-Function K659T Mutation.
Deposited
2013-02-15   Released:  2013-08-07
Deposition Author(s)
Chen, H., Mohammadi, M.
Organism(s)
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
1.8470 Å
R-Value Free
0.240
R-Value Work
0.206
4J99 From PDB

Human FGFR2 protein Secondary structure

FGFR2 Protein Interaction

Recombinant FGFR2 Protein Feature

FGFR2 Protein, Human, Recombinant (beta IIIc, His Tag)

High Purity
> 90 % as determined by SDS-PAGE.
Low Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.

Recombinant FGFR2 protein citations

Title
Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia
Year
2017
Author
Zhou, J;He, L;Pang, Z;Appelman, HD;Kuick, R;Beer, DG;Li, M;Wang, TD;
Journal
Oncotarget
Title
A two-step process for capture and purification of human basic fibroblast growth factor from E. coli homogenate: Yield versus endotoxin clearance
Year
2018
Author
Sauer, DG;Mosor, M;Frank, AC;Weiß, F;Christler, A;Walch, N;Jungbauer, A;Dürauer, A;
Journal
Protein Expr. Purif.
Title
Bioactivation of Spider Silk with Basic Fibroblast Growth Factor for in Vitro Cell Culture: A Step toward Creation of Artificial ECM
Year
2018
Author
Thatikonda, N;Nilebäck, L;Kempe, A;Widhe, M;Hedhammar, M;
Journal
ACS Biomater. Sci. Eng.

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