FABP5 (Protein | Antibody | cDNA Clone | ELISA Kit)

All FABP5 reagents are produced in house and quality controlled, including 2 FABP5 Antibody, 2 FABP5 Gene, 1 FABP5 IP Kit, 1 FABP5 Protein. All FABP5 reagents are ready to use.

FABP5 Protein (1)

    FABP5 Antibody (2)

      FABP5 cDNA Clone (2)

      NM_001444.2

      In expression vector

      In expression vector

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      FABP5 Background

      Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein which Belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Fatty acid-binding proteins ( FABPs ) are postulated to serve as lipid shuttles that solubilize hydrophobic fatty acids and deliver them to appropriate intracellular sites. E-FABP / FABP5 is predominantly expressed in keratinocytes and is overexpressed in the actively proliferating tissue characteristic of psoriasis and wound healing. E-FABP / FABP5 exhibits an important role in binding free fatty acids, as well as regulating lipid metabolism and transport. E-FABP / FABP5 has high specificity for fatty acids. It has highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity of FABP5. E-FABP / FABP5 may be involved in keratinocyte differentiation.

      FABP5 References

      • Hohoff C., et al., 1999, Biochemistry 38:12229-39
      • Gutierrez-Gonzalez L.H., et al., 2002, Biochem. J. 364:725-37.
      • Ogawa,E. et al., 2011, J Invest Dermatol. 131 (3):604-12.
      • Ma,X. et al., 2010, Mol Biol Rep. 37 (8):4003-11.

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