EPOR (Protein | Antibody | cDNA Clone | ELISA Kit)

All EPOR reagents are produced in house and quality controlled, including 8 EPOR Antibody, 2 EPOR ELISA, 26 EPOR Gene, 4 EPOR Lysate, 4 EPOR Protein, 2 EPOR qPCR. All EPOR reagents are ready to use.

EPOR Protein (4)

    EPOR Antibody (8)

      EPOR ELISA Kit & Match Antibody ELISA Pair Set (2)

      EPOR cDNA Clone (26)


      EPOR Lysate (4)

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        EPOR Background

        Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.

        EPOR References

        • Divoky V, et al. (2002) Mouse surviving solely on human erythropoietin receptor (EpoR): model of human EpoR-linked disease. Blood 99(10): 3873-4.
        • Carruthers SG. (2009) A truncated erythropoietin receptor EPOR-T is associated with hypertension susceptibility. Clin Pharmacol Ther. 86(2): 134-6.
        • Baltaziak M, et al. (2009) Relationships of P53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res. 29(10):4151-6.

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