TNFRSF10A gene / cDNA is a protein-coding gene which located on 8p21.3. The TNFRSF10A gene is conserved in chimpanzee, Rhesus monkey, cow, mouse, and rat.31 organisms have orthologs with human gene TNFRSF10A.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
DR4 / TRAIL R1 cDNA / Gene Sequence
LOCUS NM_003844 1764 bp mRNA linear PRI 15-JUL-2018
Homo sapiens TNF receptor superfamily member 10a (TNFRSF10A), mRNA.
This sequence information is just for reference only.
Successfully added to cart Please enter catalog numberSubmitted successfullyNetwork ErrorPlease enter your company namePlease enter your namePlease enter your emailPlease enter a valid email addressPlease enter some message