CD89 cDNA Clone: Expression and Clone Vector / Plasmid

CD89 cDNA / Gene Overview

FCAR gene / cDNA is a protein-coding gene which located on 19q13.42. The FCAR gene is conserved in chimpanzee, Rhesus monkey, cow, and rat.51 organisms have orthologs with human gene FCAR.

CD89 cDNA / Gene Function

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

CD89 cDNA / Gene Sequence

LOCUS
LOCUS NM_002000 2618 bp mRNA linear PRI 01-JUL-2018
DEFINITION
Homo sapiens Fc fragment of IgA receptor (FCAR), transcript variant 1, mRNA.
ACCESSION
NM_002000
VERSION
NM_002000.3

This sequence information is just for reference only.

CD89 Family & Reagents

CD89 Gene family reagents (CD molecules)

Approved Symbol Reagent list
NGFR
TEK
CD36
CD37
GYPC
ALCAM
TNFRSF10B
CD55
SELL
INSR
Approved Symbol Reagent list
KIR2DL1
FCGR2B
CD1B
SIGLEC5
CTLA4
ENTPD1
CD19
BST1
BTN3A1
IGSF8

CD89 Gene family reagents (Immunoglobulin like domain containing)

Approved Symbol Reagent list
FCRL1
FCRL2
ALCAM
CDON
CD160
SEMA3A
Tie1
CNTFR
NCR1
IL1RAPL1
Approved Symbol Reagent list
CEACAM1
THY1
VSTM1
IL12B
CD244
CADM4
PVR
ICAM3
CD48
IL11RA

CD89 cDNA / Gene Alias

  • CD89

CD89 cDNA / Gene Expression

Restricted expression toward bone marrow (RPKM 95.4)