This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
CD89 cDNA / Gene Sequence
LOCUS NM_002000 2618 bp mRNA linear PRI 01-JUL-2018
Homo sapiens Fc fragment of IgA receptor (FCAR), transcript variant 1, mRNA.
This sequence information is just for reference only.
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