CD160: CD160 Protein | CD160 Antibody

CD160 Gene family

CD160 Background

CD16 antigen, also known as Natural killer cell receptor BY55 and CD16, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD16 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD16 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD16 is expressed in spleen, peripheral blood, and small intestine. Expression of CD16 is restricted to functional NK and T cytotoxic lymphocytes. CD16 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD16+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD16+ lymphocyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymphocytes release a soluble form of CD16 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymphocyte responsiveness.

Reference for CD160

  • Barakonyi A. et al., 2004, J Immunol.173 (9): 5349-54.
  • Rabot M. et al., 2006, Transpl Immunol. 17 (1): 36-8.
  • Abecassis S. et al., 2007, J Invest Dermatol. 127?(5): 1161-6.
  • Giustiniani J.?et al., 2007, J Immunol. 178 (3): 1293-300.

CD160 Protein

CD160 protein function

Receptor showing broad specificity for both classical and non-classical MHC class I molecules. {ECO:0000269|PubMed:9973372}.

CD160 protein expression

Tissue specificity

Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.

CD160 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    181.00
  • Mass (Da)
    19.00

CD160 Antibody

There are 12 CD160 antibodies which are validated in multiple tissues with various applications, including FCM, ELISA, ELISA(Det), ELISA(Cap), IHC-P. There are 6 CD160 antibody for FCM, 5 CD160 antibody for ELISA, 1 CD160 antibody for ELISA(Det), 1 CD160 antibody for ELISA(Cap), 1 CD160 antibody for IHC-P. Among all these CD160 antibodies, there are 4 anti-CD160 mouse monoclonal antibodies , 5 anti-CD160 rabbit monoclonal antibodies , 3 anti-CD160 rabbit polyclonal antibodies . All the CD160 anbodies are produced in house and all are in stock. CD160 antibody customerized service is available.

CD160 Gene

CD160 gene / cDNA is a protein-coding gene which located on 1q21.1. The CD160 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, and rat.99 organisms have orthologs with human gene CD160.