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Anti-LAG3 Antibody


Anti-LAG3 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-LAG3 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse LAG3
Recombinant Mouse LAG3/LAG-3/CD223 Protein (Catalog#53069-M08H)
Produced in rabbits immunized with purified, recombinant Mouse LAG3/LAG-3/CD223 (rM LAG3/LAG-3/CD223; Catalog#53069-M08H; NP_032505.1; Met1-Leu442). LAG3/LAG-3/CD223 specific IgG was purified by Mouse LAG3/LAG-3/CD223 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
PBS, pH7.0 with 0.03% Proclin300
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Anti-LAG3 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-LAG3 Antibody: Alternative Names

Anti-CD223 Antibody; Anti-LAG-3 Antibody; Anti-Ly66 Antibody

LAG3 Background Information

LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells. It also acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signalling, leading to increased antigen-specific T-cell responses in vivo.
Full Name
lymphocyte-activation gene 3
  • Sigrid Hannier. et al., 1998, The Journal of Immunology. 161(8): 4058-65.
  • Triebel F. et al., 1990, J Exp Med. 171 (5): 1393-405.
  • Baixeras E. et al., 1992, J Exp Med. 176 (2): 327-37.
  • Huard B. et al., 1997, Proc Natl Acad Sci. 94 (11): 5744-9.
  • Kisielow M. et al., 2005, Eur J Immunol. 35 (7): 2081-8.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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