Anti-TRXR1 Antibody (Rabbit Polyclonal antibody) General Information
Reacts with: Human
Recombinant Human TXNRD1 / GRIM-12 protein (Catalog#13093-H07E)
Produced in rabbits immunized with purified, recombinant Human TXNRD1 / GRIM-12 (rh TXNRD1 / GRIM-12; Catalog#13093-H07E; Q16881-1; Tyr 161-Cys647). TXNRD1 / GRIM-12 specific IgG was purified by Human TXNRD1 / GRIM-12 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.