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Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-His Метка

ПаспортОбзорыСвязанные продуктыПротоколы
Rat MME Информация о продукте «Клон cDNA»
Gene_bank_ref_id:NM_012608.2
Размер кДНК:2253bp
Описание кДНК:Full length Clone DNA of Rattus norvegicus membrane metallo-endopeptidase with C terminal His tag.
Синоним гена:Nep, SFE, CD10, MGC93576, Mme
Виды:Rat
переносчик:pCMV3-C-His
Plasmid:
Участок рестрикции:
Последовательность меток:His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
Описание последовательности:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
Склад:The lyophilized plasmid can be stored at room temperature for three months.
His Tag Info

A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus of the protein.

Polyhistidine-tags are often used for affinity purification of polyhistidine-tagged recombinant proteins expressed in Escherichia coli and other prokarfyotic expression systems.

Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-His Метка on other vectors
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-GFPSpark МеткаRG80288-ACGRBS16760
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-OFPSpark МеткаRG80288-ACRRBS16760
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-Flag МеткаRG80288-CFRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-His МеткаRG80288-CHRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-Myc МеткаRG80288-CMRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, C-HA МеткаRG80288-CYRBS14710
Крыса CD10/Neprilysin Джин клон кДНК в вектор клонированияRG80288-GRBS5130
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, N-Flag МеткаRG80288-NFRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, N-His МеткаRG80288-NHRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, N-Myc МеткаRG80288-NMRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмиды, N-HA МеткаRG80288-NYRBS14710
Крыса CD10/Neprilysin Джин ORF экспрессии кДНК клона плазмидыRG80288-UTRBS14710
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Фон

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide. It exist as a membrane-bound protein and have high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.

Ссылки
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
  • Dogan, et al. (2000) CD10 and BCL-6 Expression in Paraffin Sections of Normal Lymphoid Tissue and B-Cell Lymphomas. American Journal of Surgical Pathology. 24(6): 846-52.
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    Каталог: RG80288-CH
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    Наличие2-3 weeks
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