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Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-HA Метка

    ПаспортОбзорыСвязанные продуктыПротоколы
    Крыса IL7 Информация о продукте «Клон cDNA»
    Gene_bank_ref_id:NM_013110.2
    Размер кДНК:465bp
    Описание кДНК:Full length Clone DNA of Rattus norvegicus interleukin 7 with C terminal HA tag.
    Синоним гена:Il1a, IL-1alpha
    Виды:Rat
    переносчик:pCMV3-C-HA
    Plasmid:
    Участок рестрикции:
    Последовательность меток:HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
    Описание последовательности:
    Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
    ( We provide with IL7 qPCR primers for gene expression analysis, RP300300 )
    Promoter:Enhanced CMV mammalian cell promoter
    Application:Stable or Transient mammalian expression
    Antibiotic in E.coli:Kanamycin
    Antibiotic in mammalian cell:Hygromycin
    Shipping_carrier:Each tube contains lyophilized plasmid.
    Склад:The lyophilized plasmid can be stored at room temperature for three months.
    HA Tag Info

    Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.

    The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.

    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-HA Метка on other vectors
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-GFPSpark МеткаRG80329-ACGRBS15400
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-OFPSpark МеткаRG80329-ACRRBS15400
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-Flag МеткаRG80329-CFRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-His МеткаRG80329-CHRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-Myc МеткаRG80329-CMRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, C-HA МеткаRG80329-CYRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин клон кДНК в вектор клонированияRG80329-GRBS5130
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, N-Flag МеткаRG80329-NFRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, N-His МеткаRG80329-NHRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, N-Myc МеткаRG80329-NMRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмиды, N-HA МеткаRG80329-NYRBS13340
    Крыса IL7/IL-7/Interleukin-7 Джин ORF экспрессии кДНК клона плазмидыRG80329-UTRBS13340
     Узнайте больше о векторов экспрессии,
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    Фон

    IL7, also known as interleukin 7, is a hematopoietic growth factor which belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.

    Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Ссылки
  • Watanabe M, et al. (1995) Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes.
  • J Clin Invest. 95(6):2945-53. Sawa Y, et al. (2009) Hepatic interleukin-7 expression regulates T cell responses. Immunity. 30 (3):447-57.
  • Flad HD, et al. (1996) Human follicular dendritic cells and vascular cells produce interleukin-7: a potential role for interleukin-7 in the germinal center reaction. Eur J Immunol. 26(10): 2541-4.
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