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NGF / NGFB Антитело, Кроличье моноклональное антитело

  • NGF / NGFB Antibody, Rabbit MAb, Immunohistochemistry
ПаспортОбзорыСвязанные продуктыПротоколы
Человек NGF Информация о продуктах-антителах
Иммуноген:Recombinant Human NGF / NGFB protein (Catalog#11050-HNAC)
Clone ID:D03
Тип Ig:Rabbit IgG
Концентрация:
Эндотоксин:
Состав:0.2 μm filtered solution in PBS
Подготовка:This antibody was obtained from a rabbit immunized with purified, recombinant Human NGF / NGFB (rh NGF / NGFB; Catalog#11050-HNAC; NP_002497.2; Ser122-Arg239).
Человек NGF Antibody IHC Application Image
NGF / NGFB Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human β-NGF in human brain (from 2 donors) with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Other NGF Antibody Products
Immunochemical staining of human CCNF in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
NGF/NGFB/beta-NGF Фон

Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. In addition, previous studies indicated that NGF may also have an important role in the regulation of the immune system.

Человек NGF/NGFB/beta-NGF Ссылки
  • Castellanos MR, et al. (2003) Evaluation of the neurorestorative effects of the murine beta-nerve growth factor infusions in old rat with cognitive deficit. Biochem Biophys Res Commun. 312(4): 867-72.
  • Wang TH, et al. (2008) Effects of pcDNA3-beta-NGF gene-modified BMSC on the rat model of Parkinson's disease. J Mol Neurosci. 35(2): 161-9.
  • Perrard MH, et al. (2009) Redundancy of the effect of TGFbeta1 and beta-NGF on the second meiotic division of rat spermatocytes. Microsc Res Tech. 72(8): 596-602.
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    Каталог: 11050-RD03-50
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    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
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