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NAALADL1 Антитело, Кроличьи поликлональные антитела, Antigen Affinity Purified

ПаспортОбзорыСвязанные продуктыПротоколы
Mouse NAALADL1 Информация о продуктах-антителах
Иммуноген:Recombinant Mouse NAALADL1 protein (Catalog#50937-M07H)
Clone ID:
Тип Ig:Rabbit IgG
Концентрация:
Эндотоксин:
Состав:0.2 μm filtered solution in PBS with 5% trehalose
Подготовка:Produced in rabbits immunized with purified, recombinant Mouse NAALADL1 (rM NAALADL1; Catalog#50937-M07H; Q7M758; Pro29-Leu745). NAALADL1 specific IgG was purified by Mouse NAALADL1 affinity chromatography.
Mouse NAALADL1 Руководство по использованию антител
Специфика:Mouse NAALADL1
Заявление:ELISA, IHC-P

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse NAALADL1 . The detection limit for Mouse NAALADL1 is 0.00975 ng/well.

IHC-P: 0.1-2 μg/mL

Склад:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Mouse NAALADL1 Antibody IHC Application Image
NAALADL1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
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Caption:
Immunochemical staining of mouse NAALADL1 in mouse brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other NAALADL1 Antibody Products
NAALADL1 Фон

N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidylpeptidase, is a Single-pass type I I membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus and ventral striatum. NAALADase L is a chloride-activated, membrane bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders.

Mouse NAALADL1 Ссылки
  • Stauch BL. 1989, Neurosci Lett. 100 (1-3): 295-300.
  • Shneider BL. et al., 1997, J. Biol. Chem. 272: 31006-15.
  • Pangalos MN. et al., 1999, J. Biol. Chem. 274: 8470-83.
  • Thomas AG. et al., 1999, Brain Res. 843 (1-2): 48-52.
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    Каталог: 50937-RP02-50
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