The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
SDHB cDNA ORF Clone, Mouse, N-Myc tag: Alternative Names
0710008N11Rik cDNA ORF Clone, Mouse
SDHB Background Information
Germline mutations in the succinate dehydrogenase B (SDHB) gene predispose to hereditary paraganglioma (PGL) syndrome type 4. SDHB overexpression impaired cell migration and invasion, and this effect was reversed following AMPK activation. SDHB silencing per se increases tumor cell migration/invasion and that microenvironment, as represented by CAFs, plays a pivotal role in enhancing collective migration/invasion in Pheo SDHB-silenced tumor cells, suggesting their role in increasing the tumor metastasizing potential.
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)