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Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-Flag Метка

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Human SERPINA7 Информация о продукте «Клон cDNA»
Gene_bank_ref_id:NM_000354.4
Размер кДНК:1248bp
Описание кДНК:Full length Clone DNA of Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 with C terminal Flag tag.
Синоним гена:TBG,
Виды:Human
переносчик:pCMV3-C-FLAG
Plasmid:
Участок рестрикции:
Последовательность меток:FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
Описание последовательности:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
Склад:The lyophilized plasmid can be stored at room temperature for three months.
FLAG Tag Info

FLAG-tag, or FLAG octapeptide, is a polypeptide protein tag that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography, then used to separate recombinant, overexpressed protein from wild-type protein expressed by the host organism. It can also be used in the isolation of protein complexes with multiple subunits.

A FLAG-tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a FLAG-tag to this protein allows one to follow the protein with an antibody against the FLAG sequence. Examples are cellular localization studies by immunofluorescence or detection by SDS PAGE protein electrophoresis.

The peptide sequence of the FLAG-tag from the N-terminus to the C-terminus is: DYKDDDDK (1012 Da). It can be used in conjunction with other affinity tags, for example a polyhistidine tag (His-tag), HA-tag or Myc-tag. It can be fused to the C-terminus or the N-terminus of a protein. Some commercially available antibodies (e.g., M1/4E11) recognize the epitope only when it is present at the N-terminus. However, other available antibodies (e.g., M2) are position-insensitive.

Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-Flag Метка on other vectors
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-GFPSpark МеткаHG10993-ACGRBS15400
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-OFPSpark МеткаHG10993-ACRRBS15400
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-Flag МеткаHG10993-CFRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-His МеткаHG10993-CHRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-Myc МеткаHG10993-CMRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, C-HA МеткаHG10993-CYRBS13340
Человек SerpinA7 Джин клон кДНК в вектор клонированияHG10993-MRBS5130
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, N-Flag МеткаHG10993-NFRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, N-His МеткаHG10993-NHRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, N-Myc МеткаHG10993-NMRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмиды, N-HA МеткаHG10993-NYRBS13340
Человек SerpinA7 Джин ORF экспрессии кДНК клона плазмидыHG10993-UTRBS13340
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Фон

Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein which belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3’-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone.

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Каталог: HG10993-CF
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Количество:+-
Наличие2-3 weeks
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