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Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, N-Myc Метка

ПаспортОбзорыСвязанные продуктыПротоколы
Human CR2 Информация о продукте «Клон cDNA»
Gene_bank_ref_id:NM_001877.3
Размер кДНК:3102bp
Описание кДНК:Full length Clone DNA of Homo sapiens complement component (3d/Epstein Barr virus) receptor 2 with N terminal Myc tag.
Синоним гена:C3DR, CD21, SLEB9, CR2
Виды:Human
переносчик:pCMV3-SP-N-Myc
Plasmid:
Участок рестрикции:
Последовательность меток:Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
Описание последовательности:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
Склад:The lyophilized plasmid can be stored at room temperature for three months.
Myc Tag Info

A myc tag can be used in many different assays that require recognition by an antibody. If there is no antibody against the studied protein, adding a myc-tag allows one to follow the protein with an antibody against the Myc epitope. Examples are cellular localization studies by immunofluorescence or detection by Western blotting.

The peptide sequence of the myc-tag is: N-EQKLISEEDL-C (1202 Da). It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the tag directly behind the signal peptide of a secretory protein, since it can interfere with translocation into the secretory pathway.

Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, N-Myc Метка on other vectors
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, C-GFPSpark МеткаHG10811-ACGRBS22240
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, C-OFPSpark МеткаHG10811-ACRRBS22240
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, C-Flag МеткаHG10811-CFRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, C-His МеткаHG10811-CHRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, C-Myc МеткаHG10811-CMRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, C-HA МеткаHG10811-CYRBS20190
Человек CD21 Джин клон кДНК в вектор клонированияHG10811-MRBS5130
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, N-Flag МеткаHG10811-NFRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, N-His МеткаHG10811-NHRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, N-Myc МеткаHG10811-NMRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмиды, N-HA МеткаHG10811-NYRBS20190
Человек CD21 Джин ORF экспрессии кДНК клона плазмидыHG10811-UTRBS20190
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Фон

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD21, also known as Complement component (3d / Epstein Barr virus) receptor 2 and CR2, is a member of the CD system and is a protein involved in complement system. CD21 is present on all mature B-cells and some T-cells and follicular dendritic cells. CD21 on mature B-cells form a complex called the B cell receptor complex with two other membrane proteins, CD19 and CD81. CD21 has a function in the complement system through serving as the cellular receper specific for ligands such as C3 and C4 which can be attached to foreign macromolecules in order to remove or uptake them. This results in B-cells having enhanced response to the antigen.

Ссылки
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Joseph M, et al. (1989) Structure and Function of the Complement Receptors, CR1 (CD35) and CR2 (CD21). Advanced in immunology. 46: 183-219.
  • Aubry JP, et al. (1992) CD21 is a ligand for CD23 and regulates IgE production. Nature 358: 505 - 7.
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    Каталог: HG10811-NM
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    Количество:+-
    Наличие2-3 weeks
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