CBR3 cDNA ORF Clone, Human, N-Myc tag General Information
Full length Clone DNA of Human carbonyl reductase 3 with N terminal Myc tag.
Enhanced CMV promoter
Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
The plasmid is confirmed by full-length sequencing.
Antibiotic in E.coli
Antibiotic in Mammalian cell
Stable or Transient mammalian expression
Storage & Shipping
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
CBR3 cDNA ORF Clone, Human, N-Myc tag Alternative Names
hCBR3 cDNA ORF Clone, Human;HEL-S-25 cDNA ORF Clone, Human;SDR21C2 cDNA ORF Clone, Human
CBR3 Background Information
CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).
carbonyl reductase 3
Lakhman SS. et al., 2005. Drug Metab Dispos. 33 (2): 254-7. Gerhard DS. et al., 2004, Genome Res. 14 (10B): 2121-7. Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.