Быстрый заказ

Gastric intrinsic factor / GIF Антитело, Кроличьи поликлональные антитела, Antigen Affinity Purified

  • Gastric intrinsic factor / GIF Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
ПаспортОбзорыСвязанные продуктыПротоколы
Человек GIF Информация о продуктах-антителах
Иммуноген:Recombinant Human GIF / Gastric intrinsic factor protein (Catalog#13544-H08H)
Clone ID:
Тип Ig:Rabbit IgG
Концентрация:
Эндотоксин:
Состав:0.2 μm filtered solution in PBS with 5% trehalose
Подготовка:Produced in rabbits immunized with purified, recombinant Human GIF / Gastric intrinsic factor (rh GIF / Gastric intrinsic factor; Catalog#13544-H08H; P27352-1; Met1-Tyr417). GIF / Gastric intrinsic factor specific IgG was purified by Human GIF / Gastric intrinsic factor affinity chromatography.
Человек GIF Antibody IHC Application Image
Gastric intrinsic factor / GIF Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
[Щелкните, чтобы увеличить изображение]
Caption:
Immunochemical staining of human GIF in human stomach with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to parietal cells.
Other GIF Antibody Products
Gastric intrinsic factor / GIF Фон

Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to gastric intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.

Человек Gastric intrinsic factor / GIF Ссылки
  • Gerdin AK. (2010) The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice. Acta Opthalmologica. 88:925-7.
  • AU - Berlin H, et al. (1968) ORAL TREATMENT OF PERNICIOUS ANEMIA WITH HIGH DOSES OF VITAMIN B12 WITHOUT INTRINSIC FACTOR. Acta Medica Scandinavica. 184(1-6):247-58.
  • Hewitt JE, et al. (1991) Human gastric intrinsic factor: characterization of cDNA and genomic clones and localization to human chromosome 11. Genomics. 10(2):432-40.
  • Product nameProduct name
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    Внимание: все продукты «ПРЕДНАЗНАЧЕНЫ ИСКЛЮЧИТЕЛЬНО ДЛЯ ИССЛЕДОВАНИЙ И НЕ ПРЕДНАЗНАЧЕНЫ ДЛЯ ДИАГНОСТИКИ ИЛИ ТЕРАПЕВТИЧЕСКОГО ЛЕЧЕНИЯ».