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Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-HA Метка

ПаспортОбзорыСвязанные продуктыПротоколы
Ferret CD74 Информация о продукте «Клон cDNA»
Gene_bank_ref_id:XM_004801653.1
Размер кДНК:648bp
Описание кДНК:Full length Clone DNA of Mustela putorius furo (sub-species: furo) CD74 molecule, major histocompatibility complex, class II invariant chain with C terminal HA tag.
Синоним гена:CD74
Виды:Ferret
переносчик:pCMV3-C-HA
Plasmid:
Участок рестрикции:
Последовательность меток:HA Tag Sequence: TATCCTTACGACGTGCCTGACTACGCC
Описание последовательности:
Sequencing primers:T7(TAATACGACTCACTATAGGG) BGH(TAGAAGGCACAGTCGAGG)
Promoter:Enhanced CMV mammalian cell promoter
Application:Stable or Transient mammalian expression
Antibiotic in E.coli:Kanamycin
Antibiotic in mammalian cell:Hygromycin
Shipping_carrier:Each tube contains lyophilized plasmid.
Склад:The lyophilized plasmid can be stored at room temperature for three months.
HA Tag Info

Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA-molecule corresponding to amino acids 98-106 has been extensively used as a general epitope tag in expression vectors. Many recombinant proteins have been engineered to express the HA tag, which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein. This tag facilitates the detection, isolation, and purification of the proteins.

The actual HA tag is as follows: 5' TAC CCA TAC GAT GTT CCA GAT TAC GCT 3' or 5' TAT CCA TAT GAT GTT CCA GAT TAT GCT 3' The amino acid sequence is: YPYDVPDYA.

Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-HA Метка on other vectors
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-GFPSpark МеткаFG60049-ACGRBS15400
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-OFPSpark МеткаFG60049-ACRRBS15400
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-Flag МеткаFG60049-CFRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-His МеткаFG60049-CHRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-Myc МеткаFG60049-CMRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, C-HA МеткаFG60049-CYRBS13340
Хорек CD74 Джин клон кДНК в вектор клонированияFG60049-GRBS5130
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, N-Flag МеткаFG60049-NFRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, N-His МеткаFG60049-NHRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, N-Myc МеткаFG60049-NMRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмиды, N-HA МеткаFG60049-NYRBS13340
Хорек CD74 Джин ORF экспрессии кДНК клона плазмидыFG60049-UTRBS13340
 Узнайте больше о векторов экспрессии,
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Фон

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD74, also known as HLA class2 histocompatibility antigen gamma chain and HLA-DR antigens-associated invariant chain, is a polypeptide involved in the formation and transport of MHC class2 protein. CD74 is expressed by B cells, macrophages, and Reed-Sternberg cells. When MHC class 2 protein was in the rough ER, its peptide-binding cleft was blocked by CD74 to prevent it from interacting with the endogenous peptides. CD74 also serves to facilitate MHC class2's export from ER.

Ссылки
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Moynes R, et al. (1997) A marker to distinguish atypical fibroxanthoma from malignant fibrous histiocytoma. Cancer. 79 (11): 2115-24.
  • Gabrielle FA, et al. (2008) Regulation of dendritic cell migration by CD74, the MHC class 2-associated invariant chain. Science. 322 (5908): 1705-10.
  • Leng L, et al. (2003) MIF signal transduction initiated by binding to CD74. JEM.197 (11): 1467-76.
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    Каталог: FG60049-CY
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    Наличие2-3 weeks
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