CK2 alpha cDNA ORF Clone in Cloning Vector, Rhesus

Cat: CG90444-G

Contact us:

215-583-7898
order_us@sinobiological.com
Distributors

All CK2 alpha Reagents

CRO Services

Product recommended


All CK2 alpha Reagents

CK2 alpha cDNA ORF Clone in Cloning Vector, Rhesus General Information

Gene

Species
Rhesus
NCBI Ref Seq
RefSeq ORF Size
1176 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 780A/G not causing the amino acid variation. Please check the sequence information before order.
Description
Full length Clone DNA of Rhesus casein kinase 2, alpha 1 polypeptide.

Plasmid

Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.

Screening

Antibiotic in E.coli
Ampicillin

Storage & Shipping

Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.

CK2 alpha cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

CK2 alpha Background Information

Casein kinase II subunit alpha, also known as CK II alpha, CSNK2A1 and CK2A1, is a member of the protein kinase superfamily, Ser / Thr protein kinase family and CK2 subfamily. Casein kinase II (CSNK2A1) is a serine / threonine protein kinase that phosphorylates acidic proteins such as casein. This kinase is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. Casein kinase II (CSNK2A1) is a constitutively active, ubiquitously expressed serine / threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CSNK2A1 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CSNK2A1, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CSNK2A1 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CSNK2A1 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via th phosphorylation of Akt.

Full Name
casein kinase 2, alpha 1 polypeptide
References
  • Schlpfer J, et al. (1997) A radiation hybrid framework map of bovine chromosome 13. Chromosome Res. 5(8): 511-9.
  • Wirkner U, et al. (1994) The human gene (CSNK2A1) coding for the casein kinase II subunit alpha is located on chromosome 20 and contains tandemly arranged Alu repeats. Genomics. 19(2): 257-65.
  • Wirkner U, et al. (1998) Genomic organization and promoter identification of the human protein kinase CK2 catalytic subunit alpha (CSNK2A1). Genomics. 48(1): 71-8.
  • CK2 alpha cDNA ORF Clone, Rhesus, Related Products

    Product Name Catalog#(PDF)
    CK2 alpha cDNA ORF Clone, Rhesus, untagged CG90444-UT
    CK2 alpha Lentiviral cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90444-ACGLN
    CK2 alpha cDNA ORF Clone, Rhesus, C-GFPSpark® tag CG90444-ACG
    CK2 alpha cDNA ORF Clone, Rhesus, N-GFPSpark® tag CG90444-ANG
    CK2 alpha cDNA ORF Clone, Rhesus, C-OFPSpark® tag CG90444-ACR
    CK2 alpha cDNA ORF Clone, Rhesus, N-OFPSpark® tag CG90444-ANR
    CK2 alpha cDNA ORF Clone, Rhesus, C-DDK (Flag®) tag CG90444-CF
    CK2 alpha cDNA ORF Clone, Rhesus, N-DDK (Flag®) tag CG90444-NF
    CK2 alpha cDNA ORF Clone, Rhesus, C-His tag CG90444-CH
    CK2 alpha cDNA ORF Clone, Rhesus, N-His tag CG90444-NH
    CK2 alpha cDNA ORF Clone, Rhesus, C-HA tag CG90444-CY
    CK2 alpha cDNA ORF Clone, Rhesus, N-HA tag CG90444-NY
    CK2 alpha cDNA ORF Clone, Rhesus, C-Myc tag CG90444-CM
    CK2 alpha cDNA ORF Clone, Rhesus, N-Myc tag CG90444-NM

    CK2 alpha cDNA ORF Clone, Rat, Related Products

    Product Name Catalog#(PDF)
    CK2 alpha cDNA ORF Clone in Cloning Vector, Rat RG83569-U
    CK2 alpha Lentiviral cDNA ORF Clone, Rat, C-GFPSpark® tag RG83569-ACGLN

    CK2 alpha cDNA ORF Clone, Mouse, Related Products

    Product Name Catalog#(PDF)
    CK2 alpha cDNA ORF Clone in Cloning Vector, Mouse MG50818-G
    CK2 alpha cDNA ORF Clone, Mouse, untagged MG50818-UT
    CK2 alpha cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50818-ACG
    CK2 alpha Lentiviral cDNA ORF Clone, Mouse, C-GFPSpark® tag MG50818-ACGLN
    CK2 alpha cDNA ORF Clone, Mouse, N-GFPSpark® tag MG50818-ANG
    CK2 alpha cDNA ORF Clone, Mouse, C-OFPSpark® tag MG50818-ACR
    CK2 alpha cDNA ORF Clone, Mouse, N-OFPSpark® tag MG50818-ANR
    CK2 alpha cDNA ORF Clone, Mouse, C-DDK (Flag®) tag MG50818-CF
    CK2 alpha cDNA ORF Clone, Mouse, N-DDK (Flag®) tag MG50818-NF
    CK2 alpha cDNA ORF Clone, Mouse, C-His tag MG50818-CH
    CK2 alpha cDNA ORF Clone, Mouse, N-His tag MG50818-NH
    CK2 alpha cDNA ORF Clone, Mouse, C-HA tag MG50818-CY
    CK2 alpha cDNA ORF Clone, Mouse, N-HA tag MG50818-NY
    CK2 alpha cDNA ORF Clone, Mouse, C-Myc tag MG50818-CM
    CK2 alpha cDNA ORF Clone, Mouse, N-Myc tag MG50818-NM
    CK2 alpha qPCR Primer Pairs, Mouse MP200789

    CK2 alpha cDNA ORF Clone, Human, Related Products

    Product Name Catalog#(PDF)
    CK2 alpha cDNA ORF Clone in Cloning Vector, Human HG10630-G
    CK2 alpha cDNA ORF Clone, Human, untagged HG10630-UT
    CK2 alpha cDNA ORF Clone, Human, C-GFPSpark® tag HG10630-ACG
    CK2 alpha Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag HG10630-ACGLN
    CK2 alpha cDNA ORF Clone, Human, N-GFPSpark® tag HG10630-ANG
    CK2 alpha cDNA ORF Clone, Human, C-OFPSpark® tag HG10630-ACR
    CK2 alpha cDNA ORF Clone, Human, N-OFPSpark® tag HG10630-ANR
    CK2 alpha cDNA ORF Clone, Human, C-DDK (Flag®) tag HG10630-CF
    CK2 alpha cDNA ORF Clone, Human, N-DDK (Flag®) tag HG10630-NF
    CK2 alpha cDNA ORF Clone, Human, C-His tag HG10630-CH
    CK2 alpha cDNA ORF Clone, Human, N-His tag HG10630-NH
    CK2 alpha cDNA ORF Clone, Human, C-HA tag HG10630-CY
    CK2 alpha cDNA ORF Clone, Human, N-HA tag HG10630-NY
    CK2 alpha cDNA ORF Clone, Human, C-Myc tag HG10630-CM
    CK2 alpha cDNA ORF Clone, Human, N-Myc tag HG10630-NM
    CK2 alpha qPCR Primer Pairs, Human HP100606
    info info
    添加购物车成功! 添加购物车失败!