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BMP-2 Антитело, Мышиное моноклональное антитело

  • BMP-2 Antibody, Mouse MAb, Immunofluorescence
ПаспортОбзорыСвязанные продуктыПротоколы
Человек BMP2 Информация о продуктах-антителах
Иммуноген:Recombinant Human BMP-2 protein (Catalog#10426-HNAE)
Clone ID:22
Тип Ig:Mouse IgG1
Концентрация:
Эндотоксин:
Состав:0.2 μm filtered solution in PBS with 5% trehalose
Подготовка:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-2 (rh BMP-2; Catalog#10426-HNAE; NP_001191.1; Gln283-Arg396). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Человек BMP2 Antibody IF Application Image
BMP-2 Antibody, Mouse MAb, Immunofluorescence
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Caption:
Immunofluorescence staining of Human BMP2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human BMP2 monoclonal antibody (15 µg/ml) at 37℃ 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
Other BMP2 Antibody Products
BMP-2 Фон

BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

Человек BMP-2 Ссылки
  • Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6.
  • Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.
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    Size / Price
    Каталог: 10426-MM22-50
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    Datasheet & Documentation

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